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FITC標記的血管內皮細胞遷移蛋白抗體

文字:[大][中][小] 2017-5-2    瀏覽次數(shù):1018    

                                     FITC標記的血管內皮細胞遷移蛋白抗體                                                                                                                                                
英文名稱Anti-AAMP/FITC
中文名稱:FITC標記的血管內皮細胞遷移蛋白抗體
別    名angio-associated migratory cell protein; AAMP_HUMAN.  

詳細介紹:


規(guī)格:100ul 
說 明 書100ul  
研究領域腫瘤  心血管  細胞生物  細胞粘附分子  血管內皮細胞  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產品應用Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
細胞定位細胞膜 
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AAMP (76-125aa)
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
AAMP is a 434 amino acid immunoglobulin-like protein that contains 8 WD repeats. Expressed in endothelial cells, cytotrophoblasts and blood vessels, AAMP is thought to have a heparin-sensitive role in cell adhesion and cell migration. AAMP is strongly expressed in poorly differentiated colon adenocarcinoma cells, suggesting a role for AAMP in tumor progression.

Function:
The gene product of AAMP is an immunoglobulin-type protein, which is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. The protein contains a heparin-binding domain and mediates heparin-sensitive cell adhesion.

Subcellular Location:
Cell Membrane and Cytoplasmic

Tissue Specificity:
Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cytotrophoblasts, and poorly differentiated. colon adenocarcinoma cells found in lymphatics.

Similarity:
Contains 8 WD repeats.

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