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英文名稱(chēng)Anti-NKX1-2/FITC
中文名稱(chēng)FITC標(biāo)記的轉(zhuǎn)錄因子相關(guān)蛋白NK2抗體
別 名BB238F13.2; C10orf121; Homeobox protein SAX-1; NK1 homeobox 2; NK1 transcription factor related locus 2; NK1 transcription factor-related protein 2; NKX-1.1; NKX1-2; NKX12_MOUSE; Sax1; Sax1-like; Spinal cord axial homeobox gene 1.
規(guī)格:100ug
說(shuō) 明 書(shū)100ug
研究領(lǐng)域細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng) Mouse,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
性 狀Lyophilized or Liquid
濃 度2mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse NKX1-2
亞 型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
NKX1-2 (NK1 Homeobox 2) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is NKX1-1.
Function:
May function in cell specification, particularly in the CNS.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expression detected in adult brain, testis and spleen. In the testis, expressed in the germ cells of the seminiferous epithelium, in elongating spermatids and in spermatozoa. Expressed throughout the brain with highest levels in regions of the cerebral cortex, hippocampus, diencephalon, pons, medulla and cerebellum. In the embryo, expressed in the developing posterior central nervous system. First seen in the ectoderm lateral to the primitive streak, later it encompasses the neural plate. Starting at day 9.5 pc, expressed in distinct areas of spinal cord, hindbrain, midbrain and forebrain.
Post-translational modifications:
Phosphorylated by HIPK2 in vitro.
Similarity:
Belongs to the NK-1 homeobox family.
Contains 1 homeobox DNA-binding domain.
中文名稱(chēng)FITC標(biāo)記的轉(zhuǎn)錄因子相關(guān)蛋白NK2抗體
別 名BB238F13.2; C10orf121; Homeobox protein SAX-1; NK1 homeobox 2; NK1 transcription factor related locus 2; NK1 transcription factor-related protein 2; NKX-1.1; NKX1-2; NKX12_MOUSE; Sax1; Sax1-like; Spinal cord axial homeobox gene 1.
詳細(xì)介紹：
規(guī)格:100ug
說(shuō) 明 書(shū)100ug
研究領(lǐng)域細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng) Mouse,
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
性 狀Lyophilized or Liquid
濃 度2mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse NKX1-2
亞 型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關(guān)資料：
產(chǎn)品介紹background:
NKX1-2 (NK1 Homeobox 2) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is NKX1-1.
Function:
May function in cell specification, particularly in the CNS.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expression detected in adult brain, testis and spleen. In the testis, expressed in the germ cells of the seminiferous epithelium, in elongating spermatids and in spermatozoa. Expressed throughout the brain with highest levels in regions of the cerebral cortex, hippocampus, diencephalon, pons, medulla and cerebellum. In the embryo, expressed in the developing posterior central nervous system. First seen in the ectoderm lateral to the primitive streak, later it encompasses the neural plate. Starting at day 9.5 pc, expressed in distinct areas of spinal cord, hindbrain, midbrain and forebrain.
Post-translational modifications:
Phosphorylated by HIPK2 in vitro.
Similarity:
Belongs to the NK-1 homeobox family.
Contains 1 homeobox DNA-binding domain.
